Anti-multidrug resistance

Isobavachalcone
Catalog No: CFN98593

Isobavachalcone has anti-cancer, anthelmintic, antibacterial, aphrodisiac, anti-inflammatory, astringent and antiplatelet activities, Isobavachalcone can induce apoptotic cell death in neuroblastoma via the mitochondrial pathway; it can significantly inhibit both oligomerization and fibrillization of Aβ42; it can suppress inducible nitric oxide synthase (iNOS) expression induced by macrophage-activating lipopeptide 2-kDa, polyriboinosinic polyribocytidylic acid, or lipopolysaccharide.
Lobelin
Catalog No: CFN00445

Inhalation challenge with capsaicin and rapid intravenous injection of Lobelin and alinamin indicated that peripheral c-fiber receptors were involved in the induction of coughing.
Solasonine
Catalog No: CFN90156

Solasonine displays leishmanicidal activity against promastigote forms of L. amazonensis.
Scholaricine
Catalog No: CFN97570

Scholaricine reverses multidrug resistance in vincristine-resistant KB cells.
Isoscopoletin
Catalog No: CFN97684

Isoscopoletin possesses inhibitory activity against hepatitis B virus (HBV) replication; it also shows substantial inhibition against multi-drug resistant CEM/ADR5000 cells and human CCRF-CEM leukaemia cells, with the IC50 value is 1.6 and 4.0 microM, respectively.